--- a/Lib/sysconfig.py
+++ b/Lib/sysconfig.py
@@ -558,6 +558,12 @@ def get_config_vars(*args):
         # the init-function.
         _CONFIG_VARS['userbase'] = _getuserbase()
 
+        multiarch = get_config_var('MULTIARCH')
+        if multiarch:
+            _CONFIG_VARS['multiarchsubdir'] = '/' + multiarch
+        else:
+            _CONFIG_VARS['multiarchsubdir'] = ''
+
         # Always convert srcdir to an absolute path
         srcdir = _CONFIG_VARS.get('srcdir', _PROJECT_BASE)
         if os.name == 'posix':
--- a/Lib/distutils/sysconfig.py
+++ b/Lib/distutils/sysconfig.py
@@ -112,6 +112,9 @@ def get_python_inc(plat_specific=0, pref
                 incdir = os.path.join(get_config_var('srcdir'), 'Include')
                 return os.path.normpath(incdir)
         python_dir = 'python' + get_python_version() + build_flags
+        if not python_build and plat_specific:
+            import sysconfig
+            return sysconfig.get_path('platinclude')
         return os.path.join(prefix, "include", python_dir)
     elif os.name == "nt":
         if python_build:
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -794,6 +794,7 @@ Modules/signalmodule.o: $(srcdir)/Module
 
 Python/dynload_shlib.o: $(srcdir)/Python/dynload_shlib.c Makefile
 	$(CC) -c $(PY_CORE_CFLAGS) \
+		$(if $(MULTIARCH),-DMULTIARCH='"$(MULTIARCH)"') \
 		-DSOABI='"$(SOABI)"' \
 		-o $@ $(srcdir)/Python/dynload_shlib.c
 
@@ -1477,7 +1478,7 @@ inclinstall:
 LIBPL=		@LIBPL@
 
 # pkgconfig directory
-LIBPC=		$(LIBDIR)/pkgconfig
+LIBPC=		$(LIBDIR)/$(MULTIARCH)/pkgconfig
 
 libainstall:	@DEF_MAKE_RULE@ python-config
 	@for i in $(LIBDIR) $(LIBPL) $(LIBPC); \