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diff --git a/biology/minimap2/DESCR b/biology/minimap2/DESCR new file mode 100644 index 00000000000..97ba6a1796c --- /dev/null +++ b/biology/minimap2/DESCR @@ -0,0 +1,18 @@ +Minimap2 is a versatile sequence alignment program that aligns DNA or +mRNA sequences against a large reference database. Typical use cases +include: (1) mapping PacBio or Oxford Nanopore genomic reads to the +human genome; (2) finding overlaps between long reads with error rate +up to ~15%; (3) splice-aware alignment of PacBio Iso-Seq or Nanopore +cDNA or Direct RNA reads against a reference genome; (4) aligning +Illumina single- or paired-end reads; (5) assembly-to-assembly +alignment; (6) full-genome alignment between two closely related +species with divergence below ~15%. + +For ~10kb noisy reads sequences, minimap2 is tens of times faster than +mainstream long-read mappers such as BLASR, BWA-MEM, NGMLR and +GMAP. It is more accurate on simulated long reads and produces +biologically meaningful alignment ready for downstream analyses. For +>100bp Illumina short reads, minimap2 is three times as fast as +BWA-MEM and Bowtie2, and as accurate on simulated data. Detailed +evaluations are available from the minimap2 paper +(https://doi.org/10.1093/bioinformatics/bty191). |